Procalcitonin Levels in Acute Respiratory Infection

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Can serum procalcitonin levels help interpret indeterminate chest radiographs in patients hospitalized with acute respiratory illness?

BACKGROUND Clinical diagnosis of pneumonia is difficult and chest radiographs often indeterminate, leading to incorrect diagnoses and antibiotic overuse. OBJECTIVE To determine if serum procalcitonin (ProCT) could assist in managing patients with respiratory illness and indeterminate radiographs. DESIGN Subjects were prospectively enrolled during 2 consecutive winters. SETTING A 520-bed h...

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Procalcitonin in patients with influenza A (H1N1) infection and acute respiratory failure.

OBJECTIVE To verify serum procalcitonin levels of patients with acute respiratory failure secondary to influenza A (H1N1) upon their admission to the Intensive Care Unit and to compare these results to values found in patients with sepsis and trauma admitted to the same unit. METHODS Analysis of records of patients infected with influenza A (H1N1) and respiratory failure admitted to the Gener...

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Procalcitonin guidance and reduction of antibiotic use in acute respiratory tract infection.

Increasing worldwide development of antimicrobial resistance and the association of resistance development and antibiotic overuse make it necessary to seek strategies for safely reducing antibiotic use and selection pressure. In a first step, in a non-interventional study, the antibiotic prescription rates, initial procalcitonin (PCT) levels and outcome of 702 patients presenting with acute res...

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ACP Journal Club. Meta-analysis: procalcitonin-guided antibiotic therapy reduces treatment failure in acute respiratory infection.

Review methods Cochrane Central Register of Controlled Trials (Issue 2, 2011), which includes MEDLINE and EMBASE/Excerpta Medica (May 2011) and Acute Respiratory Infections Group Specialised Register ( Jun 2011), was searched for randomized controlled trials (RCTs). Trials that exclusively focused on pediatric patients or used procalcitonin to escalate antibiotic therapy were excluded. 14 RCTs ...

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[Procalcitonin-guided antibiotic use vs. a standard approach for acute respiratory tract infection in primary care].

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ژورنال

عنوان ژورنال: Viral Immunology

سال: 2016

ISSN: 0882-8245,1557-8976

DOI: 10.1089/vim.2015.0106